mPGES1-dependent PGE(2) controls antigen-specific Th17 and Th1 responses by regulating T autocrine and paracrine PGE(2) production

The integration of inflammatory signals is paramount in controlling the intensity and duration of immune responses. Eicosanoids, particularly prostaglandin E2 (PGE(2)), are critical molecules in the initiation and resolution of inflammation and in the transition from innate to acquired immune respon...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Maseda, Damian, Johnson, Elizabeth, Nyhoff, Lindsay E., Baron, Bridgette, Kojima, Fumiaki, Wilhelm, Ashley J., Ward, Martin R., Woodward, Jerold G., Brand, David D., Crofford, Leslie J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760456/
https://ncbi.nlm.nih.gov/pubmed/29237778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601808
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