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Deletion of hypoxia-responsive microRNA-210 results in a sex-specific decrease in nephron number

Low nephron number results in an increased risk for developing hypertension and chronic kidney disease. Intrauterine growth restriction is associated with a nephron deficit in humans, and is commonly caused by placental insufficiency, which results in fetal hypoxia. The underlying mechanisms by whic...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Hemker, Shelby L, Cerqueira, Débora M, Bodnar, Andrew J, Cargill, Kasey R, Clugston, Andrew, Anslow, Melissa J, Sims-Lucas, Sunder, Kostka, Dennis, Ho, Jacqueline
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136145/
https://ncbi.nlm.nih.gov/pubmed/32141129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902767R
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