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Norrin restores blood-retinal barrier properties after vascular endothelial growth factor–induced permeability

Vascular endothelial growth factor (VEGF) contributes to blood-retinal barrier (BRB) dysfunction in several blinding eye diseases, including diabetic retinopathy. Signaling via the secreted protein norrin through the frizzled class receptor 4 (FZD4)/LDL receptor–related protein 5–6 (LRP5–6)/tetraspa...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Díaz-Coránguez, Mónica, Lin, Cheng-Mao, Liebner, Stefan, Antonetti, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7135996/
https://ncbi.nlm.nih.gov/pubmed/32086377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011273
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