Autophagy compensates for defects in mitochondrial dynamics

Compromising mitochondrial fusion or fission disrupts cellular homeostasis; however, the underlying mechanism(s) are not fully understood. The loss of C. elegans fzo-1(MFN) results in mitochondrial fragmentation, decreased mitochondrial membrane potential and the induction of the mitochondrial unfol...

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Vydáno v:PLoS Genet
Hlavní autoři: Haeussler, Simon, Köhler, Fabian, Witting, Michael, Premm, Madeleine F., Rolland, Stéphane G., Fischer, Christian, Chauve, Laetitia, Casanueva, Olivia, Conradt, Barbara
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7135339/
https://ncbi.nlm.nih.gov/pubmed/32191694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008638
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