An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2

The recognition of cis-regulatory RNA motifs in human transcripts by RNA binding proteins (RBPs) is essential for gene regulation. The molecular features that determine RBP specificity are often poorly understood. Here, we combined NMR structural biology with high-throughput iCLIP approaches to iden...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kang, Hyun-Seo, Sánchez-Rico, Carolina, Ebersberger, Stefanie, Sutandy, F. X. Reymond, Busch, Anke, Welte, Thomas, Stehle, Ralf, Hipp, Clara, Schulz, Laura, Buchbender, Andreas, Zarnack, Kathi, König, Julian, Sattler, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132250/
https://ncbi.nlm.nih.gov/pubmed/32188783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913483117
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky