טוען...
An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2
The recognition of cis-regulatory RNA motifs in human transcripts by RNA binding proteins (RBPs) is essential for gene regulation. The molecular features that determine RBP specificity are often poorly understood. Here, we combined NMR structural biology with high-throughput iCLIP approaches to iden...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7132250/ https://ncbi.nlm.nih.gov/pubmed/32188783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913483117 |
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