Načítá se...

Therapeutic and diagnostic implications of Hsp90 activation

The molecular chaperone heat-shock protein 90 (Hsp90) is involved in the stabilization and conformational maturation of many signaling proteins that are deregulated in cancers. Hsp90 inhibition results in the proteasomal degradation of these client proteins and leads to potent antitumor activity. Th...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Trends Mol Med
Hlavní autoři: Kamal, Adeela, Boehm, Marcus F, Burrows, Francis J
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Ltd. 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7128344/
https://ncbi.nlm.nih.gov/pubmed/15177193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2004.04.006
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!