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Understanding protein domain-swapping using structure-based models of protein folding

In domain-swapping, two or more identical protein monomers exchange structural elements and fold into dimers or multimers whose units are structurally similar to the original monomer. Domain-swapping is of biotechnological interest because inhibiting domain-swapping can reduce disease-causing fibril...

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Bibliographic Details
Published in:Prog Biophys Mol Biol
Main Authors: Mascarenhas, Nahren Manuel, Gosavi, Shachi
Format: Artigo
Language:Inglês
Published: Elsevier Ltd. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127520/
https://ncbi.nlm.nih.gov/pubmed/27867057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2016.09.013
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