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Structure dictates the mechanism of ligand recognition in the histidine and maltose binding proteins

Two mechanisms, induced fit (IF) and conformational selection (CS), have been proposed to explain ligand recognition coupled conformational changes. The histidine binding protein (HisJ) adopts the CS mechanism, in which a pre-equilibrium is established between the open and the closed states with the...

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Bibliografiska uppgifter
I publikationen:Curr Res Struct Biol
Huvudupphovsmän: Jayanthi, Lakshmi P., Mascarenhas, Nahren Manuel, Gosavi, Shachi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244415/
https://ncbi.nlm.nih.gov/pubmed/34235478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crstbi.2020.08.001
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