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Structure dictates the mechanism of ligand recognition in the histidine and maltose binding proteins

Two mechanisms, induced fit (IF) and conformational selection (CS), have been proposed to explain ligand recognition coupled conformational changes. The histidine binding protein (HisJ) adopts the CS mechanism, in which a pre-equilibrium is established between the open and the closed states with the...

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Detalhes bibliográficos
Publicado no:Curr Res Struct Biol
Main Authors: Jayanthi, Lakshmi P., Mascarenhas, Nahren Manuel, Gosavi, Shachi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244415/
https://ncbi.nlm.nih.gov/pubmed/34235478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crstbi.2020.08.001
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