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Structure dictates the mechanism of ligand recognition in the histidine and maltose binding proteins

Two mechanisms, induced fit (IF) and conformational selection (CS), have been proposed to explain ligand recognition coupled conformational changes. The histidine binding protein (HisJ) adopts the CS mechanism, in which a pre-equilibrium is established between the open and the closed states with the...

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Détails bibliographiques
Publié dans:Curr Res Struct Biol
Auteurs principaux: Jayanthi, Lakshmi P., Mascarenhas, Nahren Manuel, Gosavi, Shachi
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244415/
https://ncbi.nlm.nih.gov/pubmed/34235478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crstbi.2020.08.001
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