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Understanding the Folding-Function Tradeoff in Proteins
When an amino-acid sequence cannot be optimized for both folding and function, folding can get compromised in favor of function. To understand this tradeoff better, we devise a novel method for extracting the “function-less” folding-motif of a protein fold from a set of structurally similar but func...
Kaydedildi:
| Yazar: | |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625163/ https://ncbi.nlm.nih.gov/pubmed/23593437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061222 |
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