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Successes and challenges in simulating the folding of large proteins

Computational simulations of protein folding can be used to interpret experimental folding results, to design new folding experiments, and to test the effects of mutations and small molecules on folding. However, whereas major experimental and computational progress has been made in understanding ho...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Gershenson, Anne, Gosavi, Shachi, Faccioli, Pietro, Wintrode, Patrick L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952611/
https://ncbi.nlm.nih.gov/pubmed/31712314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.006794
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