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Successes and challenges in simulating the folding of large proteins

Computational simulations of protein folding can be used to interpret experimental folding results, to design new folding experiments, and to test the effects of mutations and small molecules on folding. However, whereas major experimental and computational progress has been made in understanding ho...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gershenson, Anne, Gosavi, Shachi, Faccioli, Pietro, Wintrode, Patrick L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952611/
https://ncbi.nlm.nih.gov/pubmed/31712314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.006794
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