T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections

A series of pyrazinecarboxamide derivatives T-705 (favipiravir), T-1105 and T-1106 were discovered to be candidate antiviral drugs. These compounds have demonstrated good activity in treating viral infections in laboratory animals caused by various RNA viruses, including influenza virus, arenaviruse...

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Publicado en:Antiviral Res
Main Authors: Furuta, Yousuke, Takahashi, Kazumi, Shiraki, Kimiyasu, Sakamoto, Kenichi, Smee, Donald F., Barnard, Dale L., Gowen, Brian B., Julander, Justin G., Morrey, John D.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier B.V. 2009
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127082/
https://ncbi.nlm.nih.gov/pubmed/19428599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2009.02.198
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