Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase

As anti-HCV aryl diketoacids (ADK) are good metal chelators, we anticipated that ADKs might serve as potential inhibitors of SARS CoV (SCV) NTPase/helicase (Hel) by mimicking the binding modes of the bismuth complexes which effectively competes for the Zn(2+) ion binding sites in SCV Hel thereby dis...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Bioorg Med Chem Lett
Autors principals: Lee, Chaewoon, Lee, Jin Moo, Lee, Na-Ra, Jin, Bong-Suk, Jang, Kyoung Jin, Kim, Dong-Eun, Jeong, Yong-Joo, Chong, Youhoon
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd. 2009
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127030/
https://ncbi.nlm.nih.gov/pubmed/19233643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.02.010
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars