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Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents
Nucleoside analogues that have 6-chloropurine as the nucleobase were synthesized and evaluated for anti-SARS-CoV activity by plaque reduction and yield reduction assays in order to develop novel anti-SARS-CoV agents. Among these analogues, two compounds, namely, 1 and 11, exhibited promising anti-SA...
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| Publicat a: | Bioorg Med Chem Lett |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier Ltd.
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7126875/ https://ncbi.nlm.nih.gov/pubmed/17336519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.02.026 |
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