Cargando...
Synthesis, cytotoxic activity, and SAR analysis of the derivatives of taxchinin A and brevifoliol
Twenty-one derivatives of taxchinin A (1) and brevifoliol (2) were synthesized and evaluated for cytotoxicity against human non-small lung cancer (A549) cell line. Nine derivatives showed potent activity with IC(50) values from 0.48 to 6.22 μM. 5-Oxo-13-TBDMS-taxchinin A (11) and 5-oxo-13,15-epoxy-1...
Gardado en:
| Publicado en: | Bioorg Med Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier Ltd.
2008
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7126827/ https://ncbi.nlm.nih.gov/pubmed/18381240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.03.041 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|