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Synthesis and Cytotoxicity Evaluation of Naphthalimide Derived N-Mustards
A series of N-mustards, which was conjugated to mono- or bis-naphthalimides with a flexible amine link, were synthesized and evaluated for cytotoxicity against five cancer cell lines (HCT-116, PC-3, U87 MG, Hep G2 and SK-OV-3). Several compounds displayed better activities than the control compound...
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| 發表在: | Molecules |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6271267/ https://ncbi.nlm.nih.gov/pubmed/24968335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19078803 |
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