One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation

Cyclophilin A (CypA) is a ubiquitous cellular enzyme playing critical roles in many biological processes, and its inhibitor has been reported to have potential immunosuppressive activity. In this work, we reported a novel quinoxaline derivative, 2,3-di(furan-2-yl)-6-(3-N,N-diethylcarbamoyl-piperidin...

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Publicado en:Bioorg Med Chem
Autores principales: Li, Jian, Chen, Jing, Zhang, Li, Wang, Feng, Gui, Chunshan, Qin, Yu, Xu, Qiang, Liu, Hong, Nan, Fajun, Shen, Jingkang, Bai, Donglu, Chen, Kaixian, Shen, Xu, Jiang, Hualiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Ltd. 2006
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126670/
https://ncbi.nlm.nih.gov/pubmed/16682211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.04.026
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