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Barriers to and new approaches for gene therapy and gene delivery in cystic fibrosis

Clinical trials of gene therapy for cystic fibrosis suggest that current levels of gene transfer efficiency are probably too low to result in clinical benefit, largely as a result of the barriers faced by gene transfer vectors within the airways. The respiratory epithelium has evolved a complex seri...

詳細記述

保存先:
書誌詳細
出版年:Adv Drug Deliv Rev
主要な著者: Ferrari, Stefano, Geddes, Duncan M, Alton, Eric W.F.W
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Science B.V. 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126523/
https://ncbi.nlm.nih.gov/pubmed/12458150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0169-409X(02)00145-X
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