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Barriers to and new approaches for gene therapy and gene delivery in cystic fibrosis
Clinical trials of gene therapy for cystic fibrosis suggest that current levels of gene transfer efficiency are probably too low to result in clinical benefit, largely as a result of the barriers faced by gene transfer vectors within the airways. The respiratory epithelium has evolved a complex seri...
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| Publicado no: | Adv Drug Deliv Rev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science B.V.
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7126523/ https://ncbi.nlm.nih.gov/pubmed/12458150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0169-409X(02)00145-X |
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