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Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy

A potential siRNA carrier for pulmonary gene delivery was assessed by encapsulating siRNA into biodegradable polyester nanoparticles consisting of tertiary-amine-modified polyvinyl alcohol (PVA) backbones grafted to poly(d,l-lactide-co-glycolide) (PLGA). The resulting siRNA nanoparticles were prepar...

詳細記述

保存先:
書誌詳細
出版年:J Control Release
主要な著者: Nguyen, Juliane, Steele, Terry W.J., Merkel, Olivia, Reul, Regina, Kissel, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier B.V. 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125568/
https://ncbi.nlm.nih.gov/pubmed/18619502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.06.010
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