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Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation
Pathogenic mutation in BRCA1 gene is one of the most penetrant genetic predispositions towards cancer. Identification of the mutation provides important aspect in prevention and treatment of the mutation-caused cancer. Of the large quantity of genetic variants identified in human BRCA1, substantial...
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| Publicado no: | Comput Struct Biotechnol J |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Research Network of Computational and Structural Biotechnology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7125325/ https://ncbi.nlm.nih.gov/pubmed/32257056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.03.013 |
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