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Impact of tumour size measurement inter-operator variability on model-based drug effect evaluation

PURPOSE: During oncology clinical trials, tumour size (TS) measurements are commonly used to monitor disease progression and to assess drug efficacy. We explored inter-operator variability within a subset of a phase III clinical trial conducted from August 1995 to February 1997 and its impact on dru...

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Détails bibliographiques
Publié dans:Cancer Chemother Pharmacol
Auteurs principaux: Lombard, Aurélie, Mistry, Hitesh, Chapman, Sonya C., Gueoguieva, Ivelina, Aarons, Leon, Ogungbenro, Kayode
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125250/
https://ncbi.nlm.nih.gov/pubmed/32170415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04049-5
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