In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair

The XPD helicase is a central component of the general transcription factor TFIIH which plays major roles in transcription and nucleotide excision repair (NER). Here we present the high-resolution crystal structure of the Arch domain of XPD with its interaction partner MAT1, a central component of t...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Peissert, Stefan, Sauer, Florian, Grabarczyk, Daniel B., Braun, Cathy, Sander, Gudrun, Poterszman, Arnaud, Egly, Jean-Marc, Kuper, Jochen, Kisker, Caroline
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125077/
https://ncbi.nlm.nih.gov/pubmed/32245994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15241-9
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