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Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation
The XPD protein is a vital subunit of the general transcription factor TFIIH which is not only involved in transcription but is also an essential component of the eukaryotic nucleotide excision DNA repair (NER) pathway. XPD is a superfamily-2 5′-3′ helicase containing an iron–sulphur cluster. Its he...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261550/ https://ncbi.nlm.nih.gov/pubmed/22081108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.374 |
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