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The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair

Nucleotide excision repair (NER) in eukaryotes is orchestrated by the core form of the general transcription factor TFIIH, containing the helicases XPB, XPD and five ‘structural’ subunits, p62, p44, p34, p52 and p8. Recent cryo-EM structures show that p62 makes extensive contacts with p44 and in par...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Barnett, Jamie T, Kuper, Jochen, Koelmel, Wolfgang, Kisker, Caroline, Kad, Neil M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736792/
https://ncbi.nlm.nih.gov/pubmed/33166411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa973
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