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The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair
Nucleotide excision repair (NER) in eukaryotes is orchestrated by the core form of the general transcription factor TFIIH, containing the helicases XPB, XPD and five ‘structural’ subunits, p62, p44, p34, p52 and p8. Recent cryo-EM structures show that p62 makes extensive contacts with p44 and in par...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736792/ https://ncbi.nlm.nih.gov/pubmed/33166411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa973 |
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