CD73 blockade promotes dendritic cell infiltration of irradiated tumors and tumor rejection

The ability of focal radiotherapy to promote priming of tumor-specific CD8(+) T cells and increase responses to immunotherapy is dependent on infiltration of the tumor by Batf3-dependent conventional dendritic cell type 1 (cDC1) cells. Such infiltration is driven by radiotherapy-induced IFN type I (...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Wennerberg, Erik, Spada, Sheila, Rudqvist, Nils-Petter, Lhuillier, Claire, Gruber, Sylvia, Chen, Qiuying, Zhang, Fengli, Zhou, Xi Kathy, Gross, Steven S., Formenti, Silvia Chiara, Demaria, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125001/
https://ncbi.nlm.nih.gov/pubmed/32047024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0449
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