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Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system
The expression of antigens that are recognized by self-reactive T cells is essential for immune-mediated tumor rejection by immune checkpoint blockade (ICB) therapy. Growing evidence suggests that mutation-associated neoantigens drive ICB responses in tumors with high mutational burden. In most pati...
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| Udgivet i: | Genome Med |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6587285/ https://ncbi.nlm.nih.gov/pubmed/31221199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0653-7 |
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