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Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system
The expression of antigens that are recognized by self-reactive T cells is essential for immune-mediated tumor rejection by immune checkpoint blockade (ICB) therapy. Growing evidence suggests that mutation-associated neoantigens drive ICB responses in tumors with high mutational burden. In most pati...
Gorde:
| Argitaratua izan da: | Genome Med |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
BioMed Central
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6587285/ https://ncbi.nlm.nih.gov/pubmed/31221199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0653-7 |
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