In vitro and in vivo antimicrobial activity of two α-helical cathelicidin peptides and of their synthetic analogs

Two α-helical antimicrobial peptides (BMAP-27 and -28) and four synthetic analogs were compared for in vitro and in vivo antimicrobial efficacy. All peptides proved active in vitro at micromolar concentrations against a range of clinical isolates, including antibiotic-resistant strains. BMAP-27 and...

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Bibliographic Details
Published in:Peptides
Main Authors: Benincasa, Monica, Skerlavaj, Barbara, Gennaro, Renato, Pellegrini, Antonio, Zanetti, Margherita
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7124310/
https://ncbi.nlm.nih.gov/pubmed/15019203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2003.07.025
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