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Rapid and Reliable Detection of Antimicrobial Peptide Penetration into Gram-Negative Bacteria Based on Fluorescence Quenching

In this paper, we describe a rapid flow cytometry method to identify antimicrobial peptides that are internalized into bacterial cells and differentiate them from those that are membrane active. The method was applied to fluorescently labeled Bac7(1-35) and polymyxin B, whose mechanisms of action ar...

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Hlavní autoři: Benincasa, Monica, Pacor, Sabrina, Gennaro, Renato, Scocchi, Marco
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715650/
https://ncbi.nlm.nih.gov/pubmed/19470515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01620-08
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