Mutated CEACAMs Disrupt Transforming Growth Factor beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis

BACKGROUND AND AIMS: We studied interactions among proteins of the carcinoembryonic antigen related cell adhesion molecule (CEACAM) family, which interact with microbes, and transforming growth factor beta (TGFB) signaling pathway, which is often altered in colorectal cancer cells. We investigated m...

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Publicado en:Gastroenterology
Main Authors: Gu, Shoujun, Zaidi, Sobia, Hassan, Imtaiyaz, Mohammad, Taj, Malta, Tathiane M., Noushmehr, Houtan, Nguyen, Bryan, Crandall, Keith A., Srivastav, Jigisha, Obias, Vincent, Lin, Paul, Nguyen, Bao-Ngoc, Yao, Michael, Yao, Ren, King, Charles Hadley, Mazumder, Raja, Mishra, Bibhuti, Rao, Shuyun, Mishra, Lopa
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7124154/
https://ncbi.nlm.nih.gov/pubmed/31585122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.09.023
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