Mutated CEACAMs Disrupt Transforming Growth Factor beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis

BACKGROUND AND AIMS: We studied interactions among proteins of the carcinoembryonic antigen related cell adhesion molecule (CEACAM) family, which interact with microbes, and transforming growth factor beta (TGFB) signaling pathway, which is often altered in colorectal cancer cells. We investigated m...

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Vydáno v:Gastroenterology
Hlavní autoři: Gu, Shoujun, Zaidi, Sobia, Hassan, Imtaiyaz, Mohammad, Taj, Malta, Tathiane M., Noushmehr, Houtan, Nguyen, Bryan, Crandall, Keith A., Srivastav, Jigisha, Obias, Vincent, Lin, Paul, Nguyen, Bao-Ngoc, Yao, Michael, Yao, Ren, King, Charles Hadley, Mazumder, Raja, Mishra, Bibhuti, Rao, Shuyun, Mishra, Lopa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7124154/
https://ncbi.nlm.nih.gov/pubmed/31585122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.09.023
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