Mutated CEACAMs Disrupt Transforming Growth Factor beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis

BACKGROUND AND AIMS: We studied interactions among proteins of the carcinoembryonic antigen related cell adhesion molecule (CEACAM) family, which interact with microbes, and transforming growth factor beta (TGFB) signaling pathway, which is often altered in colorectal cancer cells. We investigated m...

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Foilsithe in:Gastroenterology
Main Authors: Gu, Shoujun, Zaidi, Sobia, Hassan, Imtaiyaz, Mohammad, Taj, Malta, Tathiane M., Noushmehr, Houtan, Nguyen, Bryan, Crandall, Keith A., Srivastav, Jigisha, Obias, Vincent, Lin, Paul, Nguyen, Bao-Ngoc, Yao, Michael, Yao, Ren, King, Charles Hadley, Mazumder, Raja, Mishra, Bibhuti, Rao, Shuyun, Mishra, Lopa
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7124154/
https://ncbi.nlm.nih.gov/pubmed/31585122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.09.023
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