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Innate Resistance to Flavivirus Infections and the Functions of 2′-5′ Oligoadenylate Synthetases
Mouse susceptibility to experimental infections with flaviviruses is significantly influenced by a cluster of genes on chromosome 5 encoding a family of proteins with enzymatic properties, the 2′–5′ oligoadenylate synthetases (OAS). Positional cloning of the locus in question has revealed that susce...
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| Udgivet i: | Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunology |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7122621/ https://ncbi.nlm.nih.gov/pubmed/18727488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-540-75203-5_4 |
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