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The Ubiquitin-Proteasome System (UPS) as a Cancer Drug Target: Emerging Mechanisms and Therapeutics

The Ubiquitin-Proteasome System (UPS) plays an important role in the setting of the cellular response to multiple stress signals. Although the primary function of ubiquitin was initially associated with proteolysis, it is now considered as a key regulator of protein function controlling, among other...

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Detalhes bibliográficos
Publicado no:Stress Response Pathways in Cancer
Main Authors: Mata-Cantero, Lydia, Lobato-Gil, Sofía, Aillet, Fabienne, Lang, Valérie, Rodriguez, Manuel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7121086/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-017-9421-3_11
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