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Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities

Post-translational modification with ubiquitin is one of the most important mechanisms in the regulation of protein stability and function. However, the high reversibility of this modification is the main obstacle for the isolation and characterization of ubiquitylated proteins. To overcome this pro...

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Detalhes bibliográficos
Main Authors: Hjerpe, Roland, Aillet, Fabienne, Lopitz-Otsoa, Fernando, Lang, Valerie, England, Patrick, Rodriguez, Manuel S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775171/
https://ncbi.nlm.nih.gov/pubmed/19798103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.192
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