Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities

Post-translational modification with ubiquitin is one of the most important mechanisms in the regulation of protein stability and function. However, the high reversibility of this modification is the main obstacle for the isolation and characterization of ubiquitylated proteins. To overcome this pro...

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Autori principali: Hjerpe, Roland, Aillet, Fabienne, Lopitz-Otsoa, Fernando, Lang, Valerie, England, Patrick, Rodriguez, Manuel S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2009
Soggetti:
Scientific Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775171/
https://ncbi.nlm.nih.gov/pubmed/19798103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.192
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