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Inhibition of hepatitis B virus replication by ligand-mediated activation of RNase L
RNase L is a cellular endoribonuclease that is activated by 2′,5′-linked oligoadenylates (2–5A), which are unique and specific ligands synthesized by a family of interferon-inducible, dsRNA-activated enzymes named oligoadenylate synthetases. In the typical antiviral pathway, activated RNase L degrad...
Shranjeno v:
| izdano v: | Antiviral Res |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier B.V.
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7119188/ https://ncbi.nlm.nih.gov/pubmed/24509240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.01.021 |
| Oznake: |
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