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Construction of an infectious cDNA clone of genotype 1 avian hepatitis E virus: characterization of its pathogenicity in broiler breeders and demonstration of its utility in studying the role of the hypervariable region in virus replication

A full-length infectious cDNA clone of the genotype 1 Korean avian hepatitis E virus (avian HEV) (pT11-aHEV-K) was constructed and its infectivity and pathogenicity were investigated in leghorn male hepatoma (LMH) chicken cells and broiler breeders. We demonstrated that capped RNA transcripts from t...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Gen Virol
Κύριοι συγγραφείς: Park, Soo-Jeong, Lee, Byung-Woo, Moon, Hyun-Woo, Sung, Haan Woo, Yoon, Byung-Il, Meng, Xiang-Jin, Kwon, Hyuk Moo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Microbiology Society 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346598/
https://ncbi.nlm.nih.gov/pubmed/25593160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.000045
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