Construction of an infectious cDNA clone of genotype 1 avian hepatitis E virus: characterization of its pathogenicity in broiler breeders and demonstration of its utility in studying the role of the hypervariable region in virus replication

A full-length infectious cDNA clone of the genotype 1 Korean avian hepatitis E virus (avian HEV) (pT11-aHEV-K) was constructed and its infectivity and pathogenicity were investigated in leghorn male hepatoma (LMH) chicken cells and broiler breeders. We demonstrated that capped RNA transcripts from t...

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Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Park, Soo-Jeong, Lee, Byung-Woo, Moon, Hyun-Woo, Sung, Haan Woo, Yoon, Byung-Il, Meng, Xiang-Jin, Kwon, Hyuk Moo
Format: Artigo
Sprog:Inglês
Udgivet: Microbiology Society 2015
Fag:
Animal
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346598/
https://ncbi.nlm.nih.gov/pubmed/25593160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.000045
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