Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington’s disease pathology

BACKGROUND: Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder that affects cognitive and motor abilities by primarily targeting the striatum and cerebral cortex. HD is caused by a mutation elongating the CAG repeats within the Huntingtin gene, resulting in HTT protein mi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Savage, Julie C., St-Pierre, Marie-Kim, Carrier, Micaël, El Hajj, Hassan, Novak, Sammy Weiser, Sanchez, Maria Gabriela, Cicchetti, Francesca, Tremblay, Marie-Ève
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118932/
https://ncbi.nlm.nih.gov/pubmed/32241286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01782-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados