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Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques
A detailed protocol is provided here to identify amyloid Aβ plaques in brain sections from Alzheimer's disease mouse models before pre-embedding immunostaining (specifically for ionized calcium-binding adapter molecule 1 (IBA1), a calcium binding protein expressed by microglia) and tissue proce...
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| Veröffentlicht in: | J Vis Exp |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MyJove Corporation
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4927759/ https://ncbi.nlm.nih.gov/pubmed/27286292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54060 |
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