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Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques

A detailed protocol is provided here to identify amyloid Aβ plaques in brain sections from Alzheimer's disease mouse models before pre-embedding immunostaining (specifically for ionized calcium-binding adapter molecule 1 (IBA1), a calcium binding protein expressed by microglia) and tissue proce...

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Podrobná bibliografie
Vydáno v:J Vis Exp
Hlavní autoři: Bisht, Kanchan, El Hajj, Hassan, Savage, Julie C., Sánchez, Maria G., Tremblay, Marie-Ève
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927759/
https://ncbi.nlm.nih.gov/pubmed/27286292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54060
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