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Ultrastructural evidence of microglial heterogeneity in Alzheimer’s disease amyloid pathology

BACKGROUND: Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by the deposition of extracellular fibrillar amyloid β (fΑβ) and the intracellular accumulation of neurofibrillary tangles. As AD progresses, Aβ drives a robust and prolonged inflammatory response via it...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neuroinflammation
Hauptverfasser: El Hajj, Hassan, Savage, Julie C., Bisht, Kanchan, Parent, Martin, Vallières, Luc, Rivest, Serge, Tremblay, Marie-Ève
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469225/
https://ncbi.nlm.nih.gov/pubmed/30992040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1473-9
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