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Ultrastructural evidence of microglial heterogeneity in Alzheimer’s disease amyloid pathology

Abstract Background Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by the deposition of extracellular fibrillar amyloid β (fΑβ) and the intracellular accumulation of neurofibrillary tangles. As AD progresses, Aβ drives a robust and prolonged inflammatory respons...

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Detalhes bibliográficos
Main Authors: Hassan El Hajj, Julie C. Savage, Kanchan Bisht, Martin Parent, Luc Vallières, Serge Rivest, Marie-Ève Tremblay
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-04-01
Colecção:Journal of Neuroinflammation
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Acesso em linha:http://link.springer.com/article/10.1186/s12974-019-1473-9
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