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Disease-Associated Mutant Tau Prevents Circadian Changes in the Cytoskeleton of Central Pacemaker Neurons

A hallmark feature of Alzheimer’s disease (AD) and other Tauopathies, like Frontotemporal Dementia with Parkinsonism linked to chromosome 17 (FTDP-17), is the accumulation of neurofibrillary tangles composed of the microtubule-associated protein Tau. As in AD, symptoms of FTDP-17 include cognitive d...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Cassar, Marlène, Law, Alexander D., Chow, Eileen S., Giebultowicz, Jadwiga M., Kretzschmar, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118733/
https://ncbi.nlm.nih.gov/pubmed/32292325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00232
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