Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer’s Disease

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are promising for the treatment of Alzheimer’s disease (AD). However, their low rate of migration and survival in the brain limit their clinical applicability. This study is designed to improve the therapeutic potential of hUC-MSCs by pr...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Wang, Xinxin, Wu, Junwei, Ma, Shanshan, Xie, Ya, Liu, Hongtao, Yao, Minghao, Zhang, Yanting, Yang, Greta Luyuan, Yang, Bo, Guo, Ruixia, Guan, Fangxia
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Cellular Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118399/
https://ncbi.nlm.nih.gov/pubmed/32292331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00062
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