Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer’s Disease

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are promising for the treatment of Alzheimer’s disease (AD). However, their low rate of migration and survival in the brain limit their clinical applicability. This study is designed to improve the therapeutic potential of hUC-MSCs by pr...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Wang, Xinxin, Wu, Junwei, Ma, Shanshan, Xie, Ya, Liu, Hongtao, Yao, Minghao, Zhang, Yanting, Yang, Greta Luyuan, Yang, Bo, Guo, Ruixia, Guan, Fangxia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118399/
https://ncbi.nlm.nih.gov/pubmed/32292331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00062
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