Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer’s Disease

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are promising for the treatment of Alzheimer’s disease (AD). However, their low rate of migration and survival in the brain limit their clinical applicability. This study is designed to improve the therapeutic potential of hUC-MSCs by pr...

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Dettagli Bibliografici
Pubblicato in:Front Cell Neurosci
Autori principali: Wang, Xinxin, Wu, Junwei, Ma, Shanshan, Xie, Ya, Liu, Hongtao, Yao, Minghao, Zhang, Yanting, Yang, Greta Luyuan, Yang, Bo, Guo, Ruixia, Guan, Fangxia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cellular Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118399/
https://ncbi.nlm.nih.gov/pubmed/32292331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00062
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