DNA copy number motifs are strong and independent predictors of survival in breast cancer

Somatic copy number alterations are a frequent sign of genome instability in cancer. A precise characterization of the genome architecture would reveal underlying instability mechanisms and provide an instrument for outcome prediction and treatment guidance. Here we show that the local spatial behav...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Pladsen, Arne V., Nilsen, Gro, Rueda, Oscar M., Aure, Miriam R., Borgan, Ørnulf, Liestøl, Knut, Vitelli, Valeria, Frigessi, Arnoldo, Langerød, Anita, Mathelier, Anthony, Engebråten, Olav, Kristensen, Vessela, Wedge, David C., Van Loo, Peter, Caldas, Carlos, Børresen-Dale, Anne-Lise, Russnes, Hege G., Lingjærde, Ole Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118095/
https://ncbi.nlm.nih.gov/pubmed/32242091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0884-6
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